FUS pathology in basophilic inclusion body disease
نویسندگان
چکیده
منابع مشابه
Phenotypic variability within the inclusion body spectrum of basophilic inclusion body disease and neuronal intermediate filament inclusion disease in frontotemporal lobar degenerations with FUS-positive inclusions.
Basophilic inclusion body disease and neuronal intermediate filament inclusion disease (NIFID) are rare diseases included among frontotemporal lobar degenerations with FUS-positive inclusions (FTLD-FUS). We report clinical and pathologic features of 2 new patients and reevaluate neuropathologic characteristics of 2 previously described cases, including an early-onset case of basophilic inclusio...
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Juvenile amyotrophic lateral sclerosis (ALS) with basophilic inclusions is a well-recognized entity. However, the molecular underpinnings of this devastating disease are poorly understood. Here, we present genetic and neuropathological characterizations in two young women with fatal rapidly progressive ALS with basophilic inclusions. In one case, a germline mutation (P525L) was detected in the ...
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Premature baby unit at Southmead Hospital where she arrived 1J hours after birth. The whole of her body was found to be covered by petechial haemorrhages which in Places merged to form larger lesions resembling bruises. She had a very large spleen , and a very large liver and was thought to be very slightly jaundiced. It was soon realized that this baby had some quite unusual problem and our fi...
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ژورنال
عنوان ژورنال: Acta Neuropathologica
سال: 2009
ISSN: 0001-6322,1432-0533
DOI: 10.1007/s00401-009-0598-9